منابع مشابه
Glycodelin and differentiation in endometrium and ovary: Clinical aspects related to reproduction and epithelial ovarian cancer
...................................................................................................... 7 REVIEW OF THE LITERATURE
متن کاملAngiogenic role for glycodelin in tumorigenesis.
Angiogenesis plays an important role in neovascularization in tumors. Glycodelin, a hormone-responsive protein, has been detected in tumors of reproductive organs and is found in high levels in the plasma of subjects with gynecological malignancies. Glycodelin is also found in the endothelial cells of the umbilical cord and in the blood vessels of tumors. In this study, we tested whether glycod...
متن کاملThe role of relaxin in glycodelin secretion.
Glycodelin is a glycoprotein named for its unique carbohydrate structure. Glycodelin is produced by the secretory endometrium during the late luteal phase and returns to baseline during menses of the ensuing cycle, whereas in conceptive cycles it rapidly increases. Although progesterone and possibly estradiol are required for glycodelin production, they are not directly involved in the synthesi...
متن کاملOligosaccharides modulate the apoptotic activity of glycodelin.
GlycodelinA (GdA), a multifunctional glycoprotein secreted at high concentrations by the uterine endometrium during the early phases of pregnancy, carries glycan chains on asparagines at positions N28 and N63. GdA purified from amniotic fluid is known to be a suppressor of T-cell proliferation, an inducer of T-cell apoptosis, and an inhibitor of sperm-zona binding in contrast to its glycoform, ...
متن کاملGlycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A.
Glycodelin-A is a human amniotic fluid-derived glycoprotein with contraceptive and immunosuppressive activities. An immunoreactive form of glycodelin was detected in seminal plasma over a decade ago, but definitive characterization of this glycoprotein was not pursued. We considered it unlikely that the seminal plasma of fertile men would contain an appreciable amount of contraceptive glycodeli...
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ژورنال
عنوان ژورنال: Reproductive Medicine and Biology
سال: 2013
ISSN: 1445-5781
DOI: 10.1007/s12522-013-0144-2